Tenovi earns national ranking

Medical device maker hits No. 55 on Inc. 5000

The Tenovi Gateway Hub, pictured at right, provides a plug-and-play connection for Remote Patient Monitoring (RPM) devices such as the pulse oximeter pictured at left. (Courtesy photo)

Becoming a top-ranked private company in the United States came as a bit of a surprise to the team at Tenovi, a Portsmouth-based developer of connected medical devices.

Founded in 2020 by partners with doctorates in engineering, Tenovi was “heads down,” focusing on customers and growth, not accolades, according to Jay Lenick, chief revenue officer.

After a few years, their marketing head suggested that maybe it was time to try to be included among the Inc. 5000, the prestigious annual listing of the 5,000 fastest-growing private companies in the United States, based primarily on three-year revenue growth.

“We had no idea where we would land. In fact, I didn’t think we would even be on it,” Lenick said.

Land on it, they did. At No. 55 in the 2025 list, in fact … 55th out of 5,000.

“When we were together last summer when it came out, it was gratifying,” Lenick said. Gov. Kelly Ayotte stopped by to offer her congratulations.

Then it was back to work, back to heads down, according to Lenick.

“It was great, and then we moved on,” Lenick said. “It was like: Alright, business as usual. Let’s continue to go; you can’t read the press clippings too long.”

Tenovi specializes in remote monitoring technology that connects health-related devices directly from patients to their clinical care teams without the use of Wi-Fi or phone apps.

“That’s sort of the core here, getting data from one place to another,” Lenick said. “In the healthcare setting, that’s very important.”

Patients see their primary care physicians once or twice a year, more if there’s a chronic condition involved, which may require the addition of specialists. But what happens in between visits? How is a patient’s progress — or decline — measured on a real-time basis?

“There’s a big gap in care, and so at Tenovi we’re part of the solution that fills that gap,” Lenick said.

At the core of their technology is the Gateway Hub. About the size of a hockey puck, the hub is a plug-and-play cellular gateway designed for Remote Patient Monitoring (RPM). It eliminates the need for smartphones, Wi-Fi or apps by automatically transmitting secure, law-compliant health data directly to healthcare providers, using the best available cellular signal across all carriers to upload data to a cloud that can then be downloaded by medical professionals.

Said Lenick: “You want to be able to say: Who’s got their blood pressure in order? Is the medication working? Are you taking your medication?” The fact that the hub works asynchronically is a big factor, especially for older patients, according to Lenick. A lot of RPMs rely on syncing a Bluetooth connection to a phone app.

“You can imagine how well that went for someone in their 70s or 80s. Download an app, connect it to this every time I use it, and so that was the big challenge,” Lenick said. “What Tenovi did is we have a gateway hub that is always looking and listening for that device data.”

Any number of health-related devices can connect to Tenovi’s hub — for blood pressure, diabetes, fetal doppler, blood oxygen, thermometer, weight scale and inhaler, just to name a few.

Tenovi partners with many of these third-party device-makers. In some cases, it develops its own devices. A case in point is its creation of the Smart Pillbox.

“Sometimes we’ve looked for it and we can’t find it, like the sensor-based pillbox we built from the ground up, because everything we saw was either over-engineered or overpriced. So we built it,” Lenick said.

Upon news of Tenovi’s achievement on its Inc. 5000 ranking, Gov. Kelly Ayotte dropped in to its Portsmouth office to offer her congratulations. From left: Brad Stoll, senior vice president sales; co-founder Nizan Friedman; Ayotte; Jay Lenick, chief revenue officer; Tal Reichert, chief security officer; Janice Murphy, marketing director; and Emma DiPrizio, senior customer success manager. (Courtesy photo)

The pillbox has the look and feel of most commonly used pillboxes. Tenovi’s is equipped with sensors that track opening or refilling events. When a compartment is opened, the pillbox sends a signal through the gateway to let care teams know that a patient is on track with their medication schedule. It lights up red to remind a patient to take their medication, then turns green once the medication event was recorded and transmitted to their clinician.

It’s not a matter of what device works with its hub, according to Lenick. It’s a matter of what device works best.

“We can make any of them work. We do the integration. It’s really, we want to find the most accurate devices,” he said. “There’s FDA clearance that provides excellent guidance, but then there’s third-party validation. We go beyond FDA clearance. If somebody’s going to make a decision remotely, we want it to be as accurate as possible.”

Founders Nizan Friedman and Dan Zondervan originally connected at the University of California Irvine in the early 2000s, Friedman getting his Ph.D. in biomedical engineering, Zondervan getting his PhD in mechanical engineering. They created Flint Rehab, a medical device company specializing in neurorehabilitation in 2021, then Tenovi.

“This technology was birthed through that,” Lenick said. “Now they’re able to move beyond one small set of neuro rehab into chronic disease management.”

Zondervan, who is CEO of Flint Rehab, works in Irvine, overseeing manufacturing there for Tenovi as its chief technology officer. Friedman, as CEO of Tenovi, is a Connecticut native and oversees operations at its offices on Cate Street in Portsmouth.

“I think the culture is fantastic.

It’s very horizontal. We encourage sharing ideas. It’s not a vertical organization.

Everybody has a lot of input,” said Lenick, noting that customer input “is as valuable as anything that we do.”

A weekly call involves everyone on both coasts, according to Lenick, and they finish each call with what he calls a “clinical outcome story.” Basically, it’s a story on how their technology impacted a particular patient.

“There was a grandmother who was in Dallas, Texas, that was short of breath, and because of these alerts that were sent, they were able to intervene quickly,” Lenick said. “We love clinical outcome stories. It’s terrific for us, because it makes us feel like we have a bigger impact, and allows us to have that passion and authenticity when we go talk to clients.”

Tenovi said it supports 180-plus partners, 40-plus FDA-approved devices, and care teams in all 50 states, spanning health systems, community health centers, RPM companies, health plans, pharmacies and digital health innovators.

In addition to its Inc. 5000 ranking, it was No. 1 in the 2026 Boston Globe list of New England’s fastest-growing companies, having increased its revenues nearly 50 times, or 4,800%, from 2021 to 2024.

In a media statement after the Inc. 5000 news last August, the company said it had shipped 268,000 devices and served a quarter million patients.

“Too many patients wait months between visits, and those delays create dangerous gaps in care,” Friedman said. “Our mission is to close those gaps by simplifying remote care with connected devices that put patients first. By combining clinical integrity, seamless integration and secure, real-time data, we give care teams the tools to deliver proactive, measurable outcomes. This is just the beginning.”

Added Zondervan: “Our primary goal is to simplify remote care by providing tools that ‘just work’ for the people that matter most: patients and their clinical care teams. Landing at No. 55 on the Inc. 5000 list reinforces our belief in that approach. We’re on the right path, and we’re just getting started.”

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