A process to create human tissue and bone through 3D printing won top honors at the NH Tech Alliance’s Product of the Year competition.
The BioAssembly Bot 500 with BAB Intelligence, a robotic-based tissue fabrication and manufacturing platform, was developed by Advanced Solutions Life Sciences, a Louisville, Kentucky-based company whose research and development team is based in the Manchester Millyard. The company was a Product of the Year finalist in 2021.
During his pitch to the audience Nov. 20 at the Bank of NH Stage in Concord, Jay Hoying, partner and chief scientist, talked about the technology’s origins, which began about 5½ years ago when they met with the reconstruction surgical team at a VA hospital in Seattle.
From left: Finalists: David Fairburn from CrewHero Inc., Peter Zawadzki from YULLR, Thomas Colarusso from Bio-AI Health Inc., Carlton Brule from Lase-X, and the 2025 Product of the Year winner Jay Hoying from Advanced Solutions Life Sciences (Photo by NH Tech Alliance)
A patient had lost part of his jaw during surgery to remove a tumor on his face, making it difficult to eat, speak and express himself. Gone was his ability to smile, Hoying said.
“Perhaps most heartbreaking about this story was he was driving the school bus for his community,” Hoying said. “It was the highlight of his retirement. But he stopped driving because he was afraid he was going to scare the kids as he was driving them to and from school.”
Such reconstruction surgery usually involves taking bone from elsewhere in the body to shape a new jaw, which creates other complications, Hoying said.
“So we asked the question, what if we could reconstruct our veteran friend’s face by building a piece of living bone, matching his shape or anatomy, as well as his as his biology?” he said.
The bigger question was how could that process be replicated so they could treat more than one patient at a time?
The company’s tissue platform, which features a multi-axis robotic arm, represents more than 300,000 hours of “hard work and innovation,” Hoying said.
The technology that earned the company first place this year, which incorporates artificial intelligence, allows scientists to better communicate with the system, including through texts, to create specific workflows and operations.
“Once that’s done, the instruction sets are sent off to the robotic platform. And the manufacturing of the tissue begins here,” he said, building a living bone based on surgeon and patient requirements, up to six at a time.
The system is currently at work manufacturing bone at the VA hospital in Seattle. The company envisions hospitals and medical centers around the country and the world using the technology.
“We’re starting this within the VA system in their 170 medical centers we haven’t been to already,” Hoying said. “The goal is to rebuild faces, other tissue components, and get the smile back, so to speak, with our veteran patients.”
Advanced Life Solutions Life Sciences was one of five New Hampshire companies that competed in the live and live streamed event to an audience of over 500. Scores from the judges were weighted 50 percent with the audience vote to determine the winner. (NH Business Review editors Amanda Andrews and Mike Cote were among the judges.)
The other finalists were CrewHero from CrewHero Inc., Laser Marking Tool from Lase-X, PredictX and PredictLung from Bio-AI Health Inc., and YULLR from YULLR Inc.
“The Product of the Year competition consistently showcases the finest innovations from New Hampshire, with each year’s entries pushing the boundaries of what is possible,” said Julie Demers, executive director of the NH Tech Alliance, in a press release. “We are proud to present the groundbreaking work of New Hampshire’s innovators to hundreds of viewers both in the U.S. and globally.”
Past award winners include the Auto-injector from Pirouette Pharma, FlexNX from Geophysical Survey Systems, TU3 from Mikros Technologies, Breast Cancer Locator by CairnSurgical, SpotOn Virtual Smart Fence by OnPoint Systems, Measured Air Performance, iCAD, Inc., Wilcox Industries, Plexxi, Prosenex, Single Digits, Nanocomp Technologies, UltraVision, InsightTech Gear, Holase Incorporated, Sky-Skan, Foss Manufacturing and Therma-HEXX.
A process to create human tissue and bone through 3D printing won top honors at the NH Tech Alliance’s Product of the Year competition. The BioAssembly Bot 500, a robotic-based tissue fabrication and manufacturing platform, was developed by Advanced Solutions Life Sciences, a Louisville, Kentucky-based company whose research and development team is based in the Manchester Millyard.
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